COVID-19 - Health Research Report

Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression##!2023 | Qin S, Wang G, et al. | PLOS Genetics. 2023;19(2):e1010629. ##!http://doi.org/10.1371/journal.pgen.1010629

Ascorbate oxidase-like nanozyme with high specificity for inhibition of cancer cell proliferation and online electrochemical DOPAC monitoring##!2023 | Zhe Y, Wang J, et al. | Biosensors and Bioelectronics. 2023;220:114893. ##!http://doi.org/10.1016/j.bios.2022.114893

The Oxidative Drug Combination for Suppressing KRAS G12D Inducible Tumour Growth##!2022 | Begimbetova D, Kukanova A, et al. | Biomed Res Int. 2022;2022:9426623. ##!http://doi.org/10.1155/2022/9426623

Enhancing an Oxidative “Trojan Horse” Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside##!2022 | Burska AN, Ilyassova B, et al. | Cells. 2022;11(21):3454. ##!http://doi.org/10.3390/cells11213454

Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells##!2022 | Morante-Palacios O, Godoy-Tena G, et al. | Nucleic Acids Res. 2022;50(19):10981-10994. ##!http://doi.org/10.1093/nar/gkac941

No Effect of Vitamin C Administration on Neutrophil Recovery in Autologous Stem Cell Transplantation for Myeloma or Lymphoma: A Blinded, Randomized Placebo-Controlled Trial##!2022 | van Gorkom GNY, Boerenkamp LS, et al. | Nutrients. 2022;14(22):4784. ##!http://doi.org/10.3390/nu14224784

High-Dose Vitamin C in Advanced-Stage Cancer Patients##!2021 | Zasowska-Nowak A, Nowak PJ, et al. | Nutrients. 2021;13(3):735. ##!http://doi.org/10.3390/nu13030735

A randomized phase II trial of best supportive care with or without hyperthermia and vitamin C for heavily pretreated, advanced, refractory non-small-cell lung cancer##!2020 | Ou J, Zhu X, et al. | J Adv Res. 2020;24:175-182. ##!http://doi.org/10.1016/j.jare.2020.03.004

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes##!2019 | Gillberg L, Ørskov AD, et al. | Clin Epigenetics. 2019;11:143. ##!http://doi.org/10.1186/s13148-019-0739-5

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1##!2019 | Das AB, Kakadia PM, et al. | Blood Cancer J. 2019;9(10):82. ##!http://doi.org/10.1038/s41408-019-0242-4

Vitamin C and immune cell function in inflammation and cancer##!2018 | Ang A, Pullar JM, et al. | Biochem Soc Trans. 2018;46(5):1147-1159. ##!http://doi.org/10.1042/BST20180169

In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease##!2018 | Starczak M, Zarakowska E, et al. | J Transl Med. 2018;16:204. ##!http://doi.org/10.1186/s12967-018-1581-9

Symposium on Vitamin C##!2017 | Carr AC. | Antioxidants (Basel). 2017;6(4):94. ##!http://doi.org/10.3390/antiox6040094

Authors’ Perspective: What is the Optimum Intake of Vitamin C in Humans?##!2012 | Frei B, Birlouez-Aragon I, et al. | Critical Reviews in Food Science and Nutrition. 2012;52(9):815-829. ##!http://doi.org/10.1080/10408398.2011.649149

Schedule Dependence in Cancer Therapy: Intravenous Vitamin C and the Systemic Saturation Hypothesis##!2012 | Gonzalez MJ, Miranda Massari JR, et al. | J Orthomol Med. 2012;27(1):9-12. ##!https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031610/

Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cancer##!2003 | Coulter I, Hardy M, et al. | Agency for Healthcare Research and Quality (US); 2003.

High-Dose Vitamin C versus Placebo in the Treatment of Patients with Advanced Cancer Who Have Had No Prior Chemotherapy##!1985 | Moertel CG, Fleming TR, et al. | N Engl J Med. 1985;312(3):137-141. ##!http://doi.org/10.1056/NEJM198501173120301

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.##!1976 | Cameron E, Pauling L. | Proc Natl Acad Sci U S A. 1976;73(10):3685-3689. ##!https://www.ncbi.nlm.nih.gov/pmc/articles/PMC431183/

The orthomolecular treatment of cancer II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer##!1974 | Cameron E, Campbell A. | Chemico-Biological Interactions. 1974;9(4):285-315. ##!http://doi.org/10.1016/0009-2797(74)90019-2

Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use | Annals of Internal Medicine##!Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use | Annals of Internal Medicine. | ##!https://www.acpjournals.org/doi/full/10.7326/0003-4819-140-7-200404060-00010?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org